Organic Acids
Medchemexpress LLC ATX-II TFA | 99.7% | 4934.62 (free acid) | 1 MG
ATX-II TFA is a selective sodium channel modulator toxin. It enhances late sodium current and prevents full sodium channel inactivation, leading to persistent current fractions. This can have pro-arrhythmic effects, such as slowing intrinsic heart rate and prolonging the QT interval. It is suitable for research on atrial fibrillation and long QT syndromes.
- Selective sodium channel modulator toxin
- Enhances late sodium current
- Prevents full sodium channel inactivation
- Generates persistent current fractions
- Has a pro-arrhythmic effect
- Slows intrinsic heart rate
- Prolongs QT interval
- Suitable for research on atrial fibrillation
- Suitable for research on long QT syndrome
- Purity of 99.7%
- Molecular weight of 4934.62 (free acid)
- Appearance as a solid
- White to off-white color
Medchemexpress LLC Cys-PKHB1 TFA | 1487.88 | 10MG
Cys-PKHB1 TFA is a peptide conjugated to PKHB1, functioning as a CD47 agonist peptide and a thrombospondin-1 peptide mimic with antitumor effects. It induces mitochondrial alterations, reactive oxygen species generation, and intracellular calcium accumulation, leading to calcium-dependent cell death in breast cancer cells. This compound also activates the immune system in breast cancer cells via immunogenic cell death.
- Conjugated peptide acting as a CD47 agonist
- Thrombospondin-1 peptide mimic
- Exhibits antitumor effects
- Induces mitochondrial alterations
- Promotes reactive oxygen species (ROS) generation
- Causes intracellular calcium (Ca+) accumulation
- Leads to calcium-dependent cell death in breast cancer cells
- Activates the immune system through immunogenic cell death
Medchemexpress LLC Ms15 TFA | C66H80F3N11O7S | 5 MG
MS15 TFA is a potent and selective AKT PROTAC degrader for research use only. It effectively inhibits AKT1, AKT2, and AKT3 activities, demonstrating bioavailability in mice through intraperitoneal administration.
- Potent and selective AKT PROTAC degrader
- Inhibits AKT1, -2, and -3 activities
- IC50 values: 798 nM (AKT-1), 90 nM (AKT-2), 544 nM (AKT-3)
- Bioavailable in mice via intraperitoneal administration
- Purity of 99.82%
![Medchemexpress LLC 6-Benzothiazolamine, N-[6-[2-[(cyclohexylmethyl)amino]-4-(trifluoromethyl)phenyl]-4-pyrimidinyl]- (TFA) | 99.1% | 597.58 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000438226-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 6-Benzothiazolamine, N-[6-[2-[(cyclohexylmethyl)amino]-4-(trifluoromethyl)phenyl]-4-pyrimidinyl]- (TFA) | 99.1% | 597.58 | 25 MG
AMG 7905 TFA is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. It potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin.
- Potentiates TRPV1 channels activation by protons
- Drives reflectory inhibition of thermogenesis and tail-skin vasoconstriction
- Potently blocks channel activation by capsaicin
Medchemexpress LLC Cef20 (Tfa) | 99.3% | 1057.19 | 25 MG
CEF20 TFA is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
- High purity of 99.31%
- Molecular weight of 1057.19
- Solid appearance
- White to off-white color
- Sequence: Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val (NLVPMVATV)
- Soluble in DMSO
- Store in sealed container, away from moisture
- Powder storage: -80°C for 2 years, -20°C for 1 year
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Cpn-351 TFA | 912.11 (free base) | 1 MG
CPN-351 TFA (compound 9a) is a pentapeptide that acts as a selective antagonist of human NMUR1. Its antagonistic effect on human NMUR1 is 10 times higher than on NMUR2, making it useful in the study of inflammation.
- Selective antagonist of human NMUR1
- Antagonistic effect is 10 times higher on NMUR1 than NMUR2
- Can be used in the study of inflammation
- pA2 of 7.35 for NMUR1
- Kb of 45 nM for NMUR1
Medchemexpress LLC Lagipra peptide (TFA) | 98.2% | 5756.50 (free base) | 1 MG
LAGIPRA peptide TFA is a long-acting GIP1R agonist. It enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. This peptide has potential for the research of type 2 diabetes.
- Long-acting GIP1R agonist
- Enhances insulin sensitivity
- Reduces branched-chain amino acids (BCAAs)
- Reduces ketoacids
- Potential for type 2 diabetes research
eMolecules 17012-22-5 | AstaTech | BENZOIC ACID 4-(ACETYLAMINO)- METHYL ESTER | 0.25g | 796988864 | L10152 | 98 | MFCD00463106 | 193.202 | C10H11NO3
AstaTech | N-BOC-N-BENZYLIDENE-HYDRAZINE | 1g | 268495594 | 53433 | 97.000 | 24469-50-9 | MFCD00158497 | 220.272 | C12H16N2O2
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Medchemexpress LLC Oxalic acid | 144-62-7 | 99% | 90.03 | 1 ML
Oxalic acid is a strong dicarboxylic acid found in many plants and vegetables. It can be used as an analytical reagent and a general reducing agent. This product is suitable for laboratory chemicals and substance manufacturing applications.
- Can be used as an analytical reagent
- Acts as a general reducing agent
- Suitable for laboratory use
- Identified for the manufacture of substances
Medchemexpress LLC Astressin 2B TFA | 98.5% | 4041.69 | 1 MG
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist. It blocks protective effects mediated by CRFR2, exacerbating indomethacin-induced hemorrhagic intestinal injury in rats. This compound reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion, and upregulation of inflammatory mediators. It is an important tool molecule for investigating intestinal protective mechanisms of CRFR2.
- Highly selective CRFR2 antagonist
- Blocks anxiogenic effect of Urocortin 2
- Attenuates stress-induced anxiety-related behaviors
- Exacerbates intestinal epithelial damage in specific models
- Important tool for investigating intestinal protective mechanisms of CRFR2
Medchemexpress LLC Siynfekl Tfa | 99.9% | 1013.14 | 1 MG
SIYNFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. It is an antigenic peptide that can stimulate specific T cells in experimental settings to study competitive interactions between T cells. SIYNFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR) and can be used for the detection of CD8+ T cells.
- Can stimulate specific T cells
- Used to study competitive interactions between T cells
- Exhibits low affinity for the OT-I T cell receptor (TCR)
- Can be used for the detection of CD8+ T cells
Medchemexpress LLC Pam3CSK4 (TFA) | 112208-01-2 | 99.9% | 1852.30 | 25 MG
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist, demonstrating an EC50 of 0.47 ng/mL for human TLR1/2. This compound is a TLR1/2 heterodimer that specifically recognizes triacylated lipopeptides. It has been shown to enhance the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils against Methicillin-resistant Staphylococcus aureus (MRSA).
- Acts as a TLR1/2 agonist
- Effective at an EC50 of 0.47 ng/mL for human TLR1/2
- Recognizes triacylated lipopeptides
- Enhances antibacterial functions of GM-CSF induced neutrophils
- For research use only
- Appears as a white to off-white solid
Medchemexpress LLC Balixafortide TFA (POL6326 TFA) | 1051366-32-5 | 99.9% | 1978.16 | 25 MG
Balixafortide TFA (POL6326 TFA) is a potent, selective, and well-tolerated peptidic CXCR4 antagonist with an IC50 less than 10 nM. It demonstrates significant selectivity for CXCR4, approximately 1000-fold, over various other receptors including CXCR7. This compound effectively blocks β-arrestin recruitment and calcium flux with IC50s less than 10 nM, functioning as a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent with observed anti-cancer effects.
- Potent and selective CXCR4 antagonist
- Demonstrates high selectivity over other receptors like CXCR7
- Blocks β-arrestin recruitment and calcium flux
- Functions as a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent
- Exhibits anti-cancer effects
- Optimized for favorable mouse ADME properties
Medchemexpress LLC Diisononyl phthalate 10mM 1mL | 28553-12-0 | 418.61 g/mol | C26H42O4 | 1 ML
Diisononyl phthalate supplied as a ready-to-use 10 mM solution in DMSO (1 mL). The solution is research grade (98.0% purity), has molecular formula C26H42O4 and molecular weight 418.61 g/mol, and appears colorless to light yellow. Store at room temperature for short-term storage or frozen in solvent for extended stability.
- Ready-to-use 10 mM solution in DMSO for convenient preparation.
- Small 1 mL aliquot minimizes waste and preserves integrity.
- High purity suitable for laboratory research.
- Colorless to light yellow liquid for solution-based assays.
- Recommended storage: room temperature or frozen in solvent for longer shelf life.